FORMULASI MASKER GEL PEEL OFF EKSTRAK KULIT BUAH MAHONI (Swietenia mahagoni (L.) Jacq) DENGAN VARIASI GELLING AGENT SEBAGAI ANTI BAKTERI Propionibacterium acnes

نویسندگان

چکیده

Propionibacterium acnes merupakan bakteri penyebab jerawat. Tujuan dari penelitian ini untuk mengetahui pengaruh variasi gelling agent masker gel peel off yang paling baik antara HPMC dan karbopol dalam karakteristik uji aktivitas antibakteri terhadap acnes. Ekstraksi kulit buah mahoni menggunakan metode perkolasi dengan pelarut etanol 96%. Ekstrak diperoleh akan diformulasikan sebagai sediaan karbopol, dilakukuan Rendemen ekstrak sebesar 7,56%. Hasil skrining fitokimia menunjukkan bahwa memiliki senyawa kimia alkaloid, flavonoid, saponin tanin. Konsentrasi hambat minimum 1% diameter zona 9,77 mm. evalusi fisik telah memenuhi parameter pengujian. Pada F1 memperoleh rata-rata 5,17 mm pada F3 9,42 kategori daya sedang. analisis One Way ANOVA nilai sig 0,001< 0,05 menunjukan terdapat penghambat pertumbuhan

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ژورنال

عنوان ژورنال: Jurnal Ilmu Kedokteran dan Kesehatan : Journal of Medical and Health Sciences

سال: 2022

ISSN: ['2355-7583', '2549-4864']

DOI: https://doi.org/10.33024/jikk.v9i2.5496